The Double Legacy of Joanna Blalock: Where to Start?
If you are looking to dive into the work of Leonard Goldberg, you will encounter a unique literary puzzle: there are actually two distinct book series featuring a protagonist named Joanna Blalock. The first is a series of nine contemporary medical thrillers published between 1992 and 2003. The second is a historical mystery series starting in 2017 called The Daughter of Sherlock Holmes. Because the two series are set in entirely different eras and genres, readers have two primary entry points depending on their personal tastes.
For fans of forensic pathology, medical conspiracies, and classic 1990s suspense in the vein of Patricia Cornwell or Robin Cook, the best starting point is Deadly Medicine (1992), which kicks off the contemporary series. If you prefer historical mysteries, Victorian detective work, and classic Holmesian deduction, you should start with The Daughter of Sherlock Holmes (2017). Because the historical series serves as a thematic prequel, you do not need to read the medical thrillers to enjoy the Sherlockian spin-offs, and vice versa.
The Contemporary Joanna Blalock Series (1992–2003)
The original contemporary series follows Dr. Joanna Blalock, a brilliant, strong-willed forensic pathologist based at a major hospital in Los Angeles. Goldberg, a real-life clinical professor of medicine at UCLA and an expert witness in medical malpractice suits, loaded these novels with realistic medical procedures, forensic detail, and bioethical dilemmas. The series is heavily character-driven, charting Joanna's evolving and sometimes complicated professional and romantic partnership with LAPD detective Jake Sinclair.
Over nine novels, Joanna tackles everything from organ transplant rings and rogue genetic editing to weaponized viruses. While these books capture the cutting-edge science of their era, modern readers should note that they reflect the technology of the 1990s and early 2000s, meaning pages are filled with pager beeps, payphones, and dial-up internet rather than smartphones and modern databases.
The Prequel Spin-Off: The Daughter of Sherlock Holmes (2017–Present)
In 2017, Goldberg launched a brand new historical series set on the eve of World War I. This series stars a different Joanna Blalock—a highly observant, brilliant young woman who discovers she is the biological daughter of Sherlock Holmes and Irene Adler. Set in London starting in 1914, this Joanna teams up with an elderly Dr. John Watson and his son, Dr. John Watson Jr. (who eventually becomes Joanna's husband), to apply her inherited deductive genius to cases of national security, murder, and treason.
This series is a treat for fans of the original Arthur Conan Doyle canon, blending classic Holmesian tropes with Goldberg's signature interest in early forensic science and medicine.
The DNA of Deduction: How the Two Series Connect
The connection between the Edwardian detective and the modern forensic pathologist is both genetic and meta-textual. Goldberg created the historical series after a book critic remarked that his contemporary medical thrillers 'flew along on the Holmesian wings of Joanna Blalock.' Intrigued by the comparison, Goldberg decided to make the connection literal.
In the shared universe of these books, the historical Joanna Blalock is the biological grandmother of the modern-day Joanna Blalock. According to the family timeline established by Goldberg, the historical Joanna (Holmes's daughter) and Dr. John Watson Jr. had a son who served as a fighter pilot in the Royal Air Force during World War II. Following the war, this son immigrated to San Francisco, became a banker, and later fathered the modern-day Dr. Joanna Blalock. In this way, the modern pathologist's extraordinary powers of observation and deduction are framed as genetic traits passed down from Sherlock Holmes himself.
Complete Publication Order
The Contemporary Medical Thrillers
- Deadly Medicine (1992) – Joanna investigates a series of unexplained deaths targeting nurses at a Los Angeles hospital.
- A Deadly Practice (1994) – Joanna faces a killer targeting doctors amidst a high-stakes medical malpractice suit.
- Deadly Care (1996) – A complex conspiracy involving health insurance fraud and murder.
- Deadly Harvest (1997) – Joanna uncovers an illegal organ transplant ring.
- Deadly Exposure (1998) – A bio-thriller involving a deadly virus frozen in the Arctic ice.
- Lethal Measures (2000) – A race to stop a domestic terrorist planning a biological attack.
- Fatal Care (2001) – A dive into the dark and dangerous world of experimental gene therapy.
- Brainwaves (2002) – A thriller centered on neurological experiments and selective memory removal.
- Fever Cell (2003) – Joanna investigates a lethal mystery involving a mysterious cancer treatment.
The Daughter of Sherlock Holmes Mysteries
- The Daughter of Sherlock Holmes (2017) – Joanna is introduced and recruited to solve a mysterious death at a country estate.
- A Study in Treason (2018) – A search for stolen British treaty documents on the eve of the Great War.
- The Disappearance of Alistair Ainsworth (2019) – Joanna must locate a missing codebreaker critical to the war effort.
- The Art of Deception (2020) – A murder investigation at a remote asylum housing high-profile patients.
- The Abduction of Pretty Penny (2021) – Joanna investigates the disappearance of a popular music hall performer.
- The Blue Diamond (2022) – A search for a missing legendary gemstone and a double murder.
- The Wayward Prince (2023) – A sensitive investigation into the murder of a high-ranking royal figure.
- A Scandalous Affair (2025) – Set in 1918, Joanna investigates a blackmail scheme targeting the Chancellor of the Exchequer.
Reading Guidance and Standalone Potential
In both series, the individual mysteries are self-contained and resolved by the end of each book. This means you can technically read any of the novels as standalones without feeling completely lost. However, reading them in order of publication is highly recommended because of the character development. In the contemporary series, the slow-burn relationship between Joanna Blalock and Jake Sinclair progresses significantly from book to book. Similarly, in the historical series, Joanna's integration into the Watson family, her marriage, and her growing reputation as a consulting detective build continuously over the course of the novels.
What to Know Before You Start
When starting the contemporary series, be prepared for a distinct 1990s atmosphere. The pacing is fast, but the forensic tools and societal dynamics reflect the decade in which they were written. In the historical series, the tone shifts to a cozy, traditional mystery style that mimics the pacing and speech patterns of early 20th-century historical fiction. Both series showcase Goldberg's medical expertise, ensuring that whether Joanna is analyzing blood splatters in a modern morgue or examining poison residues in a London manor, the science remains grounded in reality.